This paper discusses some of the teachings and reflections from Qur'an and Sunnah about science, engineering, technology, and management. Qur'an and Sunnah provide complete guidance about every thing, and invite mankind for observation, thinking, understanding the creation, and acquiring the knowledge. Some Ayat and Ahadith which mention some basic tools and techniques and some related to modern theories and trends are also quoted. As a result of new spirit of inquiry and struggle, the Muslim scientists developed the method of controlled experiment and other techniques which form the basis of modern science, engineering and technology. They also wrote a good number of highly valuable books. That knowledge was transferred to Europe, where it was advanced further, but without guidance of Qur'an and Sunnah. This resulted in certain material benefits but gave rise to adverse effects related to belief and moral aspects. In order to safeguard these aspects, an important aspect of Tawheed is presented which explains the reality of cause and effect phenomena.